Antiemetic Therapy

Antiemetic Therapy

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Prevention and treatment of nausea and emesis are important issues in a patients wellbeing in the clinical setting as well as for the outpatient. Various and still partly unresolved pathomechanisms play a role in nausea and emesis in humans. It is therefore important to compare results from preclinical research in animal models with results from clinical studies. This book combines an overview of the preclinical research on antiemetic drugs and state-of-the art reviews on the prevention and treatment of nausea and emesis. Established treatment regimens are compared with new interesting compounds in clinical trials. An up-to-date overview of the selection of antiemetic drugs, of their dosage and route of administration is given for clinical conditions such as emetogenic anti-cancer chemotherapy, radiation therapy, surgery, and hyperemesis gravidarum. The treatment of nausea and emesis in opioid therapy and in motion sickness is equally outlined. Whereas this book should serve the clinician in making the right choice for every patients need, it also pays significant attention to the interests of scientists in the fields of oncology, nutrition, gastroenterology, obstetrics and gynecology as well as anaesthesia.However, the recent published guidelines for the use of antiemetics, differ somewhat both in classifying radiation emetogenic risk ... of the IGARR observational trial, in my opinion, MASCC guidelines should be considered for the prescription of antiemetics in clinical practice. ... as in the treatment of highly emetogenic chemotherapy, dexamethasone should be added to the 5-HT3 antagonist for categoriesanbsp;...

Title:Antiemetic Therapy
Author:Josef Donnerer
Publisher:Karger Medical and Scientific Publishers - 2003-01-01


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