Written by the worldas foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume. Coverage begins with a review of risk factors and prevention, emphasizing lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included.Disruption of the plaques facilitates the interaction between the flowing blood and the deeper components of lipid-rich ... Apoptosis may directly affect blood thrombogenicity through the release of apoptotic cells and microparticles into the bloodstream (39). ... the direction of blood flow, whereas those exposed to low shear stress (or cultured in static condition) do not change their shape or orientation (Fig.
|Title||:||Atherothrombosis and Coronary Artery Disease|
|Author||:||Valentin Fuster, Eric J. Topol, Elizabeth G. Nabel|
|Publisher||:||Lippincott Williams & Wilkins - 2005|