Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover uracil DNA glycosylases, repair of oxidized purines in DNA, mammalian mismatch-specific DNA glycosylases, repair of apurinic/apyrimidic sites in DNA by AP endonucleases, mutagenesis of abasic sites, a prooxidized purines such as 2, 6-diamino-4- hydroxy-5-formamidopyrimidine (Fapy- G), 4, 6-diamino-5-formamidopyrimidine (Fapy-A), and 7, 8-dihydro-8-oxoadenine (8-OxoA) and 2-hydroxyadenine (2-OH-A) have been identified in y-irradiatedanbsp;...
|Title||:||Base Excision Repair of DNA Damage|
|Author||:||Ian D. Hickson|
|Publisher||:||Springer Science & Business Media - 1997-01-01|