Cardiovascular Aspects of Marfan Syndrome

Cardiovascular Aspects of Marfan Syndrome

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Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the eyes, skeleton, blood vessels, and various structures of the heart. Since 1943, when the cardiovascular manifestations of Marfan Syndrome were first described, understanding of its nature, diagnostic tools, and surgical treatment have been remarkably improved. Although the specific surgical procedures have reached an advanced standard and general acceptance, many questions remain unanswered and have given rise to ongoing controversy. Cardiovascular Aspects of Marfan Syndrome presents the advances in understanding the cause and pathogenesis of Marfan Syndrome and its current specific surgical therapy.At one stage, we used to plicate the root, now we do not even plicate the root because you put it right down on the fibrous annulus. ... You mentioned that the trend is now toward valve repair if possible, but on the other hand, we have to be reminded ... large was the diameter of the homograft which failed late, and also the technique you use for aortic valve replacement ... lacking even the myxomatous degeneration, like what happens in the mitral valve, it is the best choice to preserve it.

Title:Cardiovascular Aspects of Marfan Syndrome
Author:Roland Hetzer, Petra Gehle, Jürgen Ennker
Publisher:Springer Science & Business Media - 2012-12-06


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