Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease, will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.diabetes compared to counterparts whose work schedule is restricted to day shifts only (Mikuni et al., 1983). ... glucose homeostasis in controlled laboratory settings in healthy human volunteers (Scheer et al., 2009; Buxton et al., 2012). ... of the LD cycle and vice versa, thus designed to recapitulate conditions associated with human shift work (Husse et al., 2012). ... and the betaacell ( Marcheva et al., 2010), tissues critical for maintenance of proper glucose control in health and T2DM.
|Author||:||Christopher S. Colwell|
|Publisher||:||John Wiley & Sons - 2015-03-16|