Lastly, I determined if/how DNA repair status can influence the ionizing radiation induced bystander effect (BSE). I was able to determine that at least some of the DNA repair proteins are critical in the generation of a bystander signal providing the first evidence that DNA repair can have an influence via an inter-cellular pathway.Figure 1: human metaphase chromosome illustrating differential aquot;harlequinaquot; staining pattern; arrows indicate SCE. ... It is not clear what DNA repair pathways, or what specific proteins in these pathways, are actually involved in the formation ofanbsp;...
|Title||:||DNA Repair and Sister Chromatid Exchange|
|Author||:||R. Tanner Hagelstrom|
|Publisher||:||ProQuest - 2008|