Fetal treatment, particularly complex fetal therapy, is an emergent and expanding field. This comprehensive text focuses on areas of fetal disease and pathophysiology that can be treated in utero and the benefits and problems with such therapy. Both medical (non-invasive) and surgical procedures are discussed, drawing on the expertise of an internationally renowned author team. Each chapter includes a comprehensive overview of the basic science underlying fetal pathology, as well as discussing the highest level of technical performance of fetal interventions. Contributions from fetal therapy 'centers-of-excellence' around the world collectively emphasize the need for an evidence-based approach to the field. This volume is useful both as a quick reference guide to the latest fetal therapy options and as an in-depth study book for maternal-fetal medicine and neonatology specialists at any stage of their career who are seeking to acquire essential background knowledge. Indispensable on any bookshelf in fetal medicine units.Obesity is defined as a body mass index (BMI) of greater than 30. ... Recent work has suggested that valproic acida#39;s potent histone deacetylase inhibitory activity may disturb the balance of protein ... This makes some biological sense as topiramate also inhibits histone deacetylases much as valproic acid does, and thereforeanbsp;...
|Author||:||Mark D. Kilby, Anthony Johnson, Dick Oepkes|
|Publisher||:||Cambridge University Press - 2012-12-13|