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This reference volume follows the Fructose-2, 6-P2 story from its discovery in 1980 to current studies on the enzyme systems responsible for its synthesis and degradation. The book begins with a historical perspective on the discovery of the compound and then proceeds to its chemistry and number of derivatives. It includes a detailed treatment of the role of the compound in the regulation of carbohydrate metabolism in various tissues and organisms. A portion of this work is devoted to characterization of the enzyme activities responsible for its synthesis and degradation. This detailed, yet comprehensive work is helpful for all biochemists, experimental biologists, and biophysicists.As far as phosphorylation effects, there is no concensus as to whether phosphorylation affects the kinetics of the enzyme. ... reports on the rat liver enzyme (e.g., Reference 82) do not even mention the uniqueness of this example . D. Yeastanbsp;...

Author:Simon J. Pilkis
Publisher:CRC Press - 1990-03-20


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