A collection of cutting-edge computational tools and experimental techniques to study how genes are regulated, and to reconstruct the regulatory networks through which various cell-types are produced. On the computational side, web-based technologies to localize genes, to access and retrieve data from microarray databases, to conduct comparative genomics, and to discover the potential genomic DNA that may control the expression of protein-coding genes. Detailed experimental techniques described include methods for studying chromatin structure and allele-specific gene expression, methods for high-throughput analysis to characterize the transcription factor binding elements, and methods for isolating and identifying proteins that interact with DNA.If problems are encountered here, we advise the user to try a different web browser or make sure that JAVA is supported ... Zhang, Z. and Gerstein, M. (2003 ) Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements.
|Title||:||Gene Mapping, Discovery, and Expression|
|Publisher||:||Springer Science & Business Media - 2006-01-01|