Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An overview of the four major pathways of homologous recombinational repair is followed by a description of the several mechanisms of nonhomologous end-joining. Designed as a textbook for advanced undergraduate and graduate students with a molecular biology and genetics background, researchers and practitioners, especially in cancer biology, will also appreciate the book as a reference.... Xiaohua Wu, Zixhi Zhou, Cherry Wu, Kaiming Sun, Giovanni Bosco, Ayelet Arbel-Eden, Eliyahu Kraus, Kent Moore, MA³nica ... I first started working on a version of this book as a John Simon Guggenheim Fellow in 2000, but that effort soon faltered as I ... I didna#39;t resume serious work on this book until I was a Fellow of the Radcliffe Institute for Advanced Study in 2008. ... I am particularly indebted to Susan Lovett, my DNA repair colleague, and to Jeffrey Hall, whoawhen I first started toanbsp;...
|Author||:||James E. Haber|
|Publisher||:||Garland Science - 2013-12-16|