Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.An understanding of the strengths, weaknesses and practical application of assay methods, instrumental analysis and robotics are ... If the technical requirements are not enough of a challenge, the pressure of a screening laboratory also requires ... The human element is discussed in the operation of a centralized robotics HTS core facility (J. Babiak, chapter 28). ... R. Bryant, Schering Plough; C. Homan, Boehringer Ingelheim; D. Hook, Bristol-Myers Squibb; M. Wildey, Johnson andanbsp;...
|Title||:||High Throughput Screening|
|Author||:||John P. Devlin|
|Publisher||:||CRC Press - 1997-05-06|