Subcutaneous administration does not carry the same rare anaphylaxis risk as the intravenous route, but the onset of action is ... Because of this, the volume of FFP required to reverse a high INR to below 1.5 is often 800-3500 ml. ... Optimal PCC dosing (INR-based versus standardized fixed dose) remains somewhat controversial, although individualized dosing may ensure INR correction more rapidly.
|Title||:||Intensive Care in Neurology and Neurosurgery|
|Author||:||Daniel Agustin Godoy|
|Publisher||:||SEEd - 2013-03-01|