This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.Nat Struct Mol Biol 12:233a237 Shimon L, Hynes GM, McCormack EA, Willison KR, Horovitz A (2008) ATP-induced allostery in the ... J Biol Chem 279:16368a 16376 Tehver R, Chen J, Thirumalai D (2009) Allostery wiring diagrams in the transitions that drive the GroEL ... J Mol Biol 243:397a401 Yifrach O, Horovitz A ( 1995) Nested cooperativity in the ATPase activity of the oligomeric chaperonin GroEL.
|Author||:||Maria Armenia Carrondo, Paola Spadon|
|Publisher||:||Springer Science & Business Media - 2011-11-30|