Mechanisms and Management of COPD Exacerbations

Mechanisms and Management of COPD Exacerbations

4.11 - 1251 ratings - Source

Chronic obstructive pulmonary disease (COPD) is an increasingly important health problem world-wide. Whereas most other leading diseases have shown a decline in the past decades, COPD morbidity and mortality is on a steady increase. Exacerbations are usually defined as an increase in cough, a change in the colour or quantity of sputum, and a worsening dyspnea. The role of bacterial infections and the efficacy of antimicrobial therapy in acute exacerbations of chronic bronchitis (AECD) is still controversial. Exacerbations of chronic bronchitis are a common occurrence in clinical practice and are a leading cause of antibiotic prescription among respiratory infections. It is still uncertain whether each new exacerbation may deteriorate the natural history of chronic bronchitis. Undoubtedly, every episode includes a temporary worsening in lung function and may therefore pose the threat of respiratory failure or death in more severely obstructed patients.Potential benefits of antibiotic therapy for acute exacerbations of chronic bronchitis Immediate, short-term benefits ... an earlier return to work Prevent progression to pneumonia from severe tracheobronchial infection Long-term benefits Preventanbsp;...

Title:Mechanisms and Management of COPD Exacerbations
Author:L. Allegra, F. Blasi
Publisher:Springer Science & Business Media - 2012-12-06


You Must CONTINUE and create a free account to access unlimited downloads & streaming