These data indicate that proline 132 plays a critical role in subunit interaction and mutual subunit activation. ... However, the effect of a specific amino acid replacement on stability highly depends on the location of the mutation site and its environment in the protein structure. ... However, the same substitution at position 103 (Prol03 aquot;* Gly) does not affect h- lysozyme stability, and the thermodynamicanbsp;...
|Title||:||Memoirs of the Institute for Protein Research, Osaka University|
|Author||:||Ōsaka Daigaku. Tanpakushitsu Kenkyūjo|