In 2007, scientists estimated the direct cost of diseases associated with mould and dampness on the US population to be in the range of 4 billion dollars, and the indirect costs of lost work and school days are gauged even higher. The US Centers for Disease Control recently concluded that elimination of moisture and mouldy materials in the home definitively results in improved health. Unfortunately, problems of accurate assessment and precise identification plague the full understanding of the effects of mould on human health. Addressing exposure assessment and identification, Microorganisms in Home and Indoor Work Environments: Diversity, Health Impacts, Investigation, and Control, Second Edition discusses the methodology for conducting investigations on indoor environments, including details on key fungi and actinobacteria, and reflects advances in predicting their occurrence in buildings in various parts of the world. Beginning with a review of types of microorganisms in outdoor and indoor air, their growth and control in home and work environments, and their role in respiratory disease, this second edition presents new studies on pollen and its allergenic effects, the mechanistic basis for the effects of toxins and inflammatory agents on lung biology, and the use of molecular methods for determining microbial contaminants. On the practical side, this edition examines remediation, control, and quality assurance; occupational exposures in a wide range of environments; and infectious fungi and bacterial endotoxins in the built environment. Bringing together the state-of-the-science in this health-critical field, this accurate and timely book offers researchers, public health officials, and industrial hygienists crucial information on specific microorganisms in the built environment, along with current measurement and assessment solutions to clean up indoor air and keep residents and workers healthy in the future.This TaqMan-based qPCR methodology was extended over subsequent years into a broad ranging methodology encompassing many major indoor ... In conjunction, key studies considered how best to extract DNA for qPCR and related PCRbased analyses of indoor fungi (Williams et al. ... Similar restrictions do not, however, apply to the use of these sequences for non-commercial, research purposes.
|Title||:||Microorganisms in Home and Indoor Work Environments|
|Author||:||Brian Flannigan, Robert A. Samson, J. David Miller|
|Publisher||:||CRC Press - 2011-04-13|