Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular response to DNA injury. Given the importance of therapies that induce DNA injury in the management of human disease, this book is timely and relevant for basic and translational researchers, as well as clinicians alike.Radiology 242:244a251 Rothkamm K, Lobrich M (2003) Evidence for a lack of DNA double-strand break repair in human cells ... Proc Natl Acad Sci USA 100: 5057a5062 Rube CE, Grudzenski S, Kuhne M et al (2008) DNA double-strand break repair of blood lymphocytes and normal tissues ... Nat Rev Cancer 3:155a 168 Shroff R, Arbel-Eden A, Pilch D et al (2004) Distribution and dynamics of chromatinanbsp;...
|Title||:||Molecular Determinants of Radiation Response|
|Author||:||Theodore L. DeWeese, Marikki Laiho|
|Publisher||:||Springer Science & Business Media - 2011-03-23|