Multimodal Imaging in Neurology

Multimodal Imaging in Neurology

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The field of brain imaging is developing at a rapid pace and has greatly advanced the areas of cognitive and clinical neuroscience. The availability of neuroimaging techniques, especially magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG) and magnetic source imaging (MSI) has brought about breakthroughs in neuroscience. To obtain comprehensive information about the activity of the human brain, different analytical approaches should be complemented. Thus, in qintermodal multimodalityq imaging, great efforts have been made to combine the highest spatial resolution (MRI, fMRI) with the best temporal resolution (MEG or EEG). qIntramodal multimodalityq imaging combines various functional MRI techniques (e.g., fMRI, DTI, and/or morphometric/volumetric analysis). The multimodal approach is conceptually based on the combination of different noninvasive functional neuroimaging tools, their registration and cointegration. In particular, the combination of imaging applications that map different functional systems is useful, such as fMRI as a technique for the localization of cortical function and DTI as a technique for mapping of white matter fiber bundles or tracts. This booklet gives an insight into the wide field of multimodal imaging with respect to concepts, data acquisition, and postprocessing. Examples for intermodal and intramodal multimodality imaging are also demonstrated. Table of Contents: Introduction / Neurological Measurement Techniques and First Steps of Postprocessing / Coordinate Transformation / Examples for Multimodal Imaging / Clinical Aspects of Multimodal Imaging / References / BiographyHydrogel-based marker chips show up in MRI scans as ring structures (see arrows) and can be located manually by the ... Results The fMRI data during the motor activation paradigm were recorded according to the protocol described above.

Title:Multimodal Imaging in Neurology
Author:Hans-Peter Muller, Jan Kassubek
Publisher:Morgan & Claypool Publishers - 2008


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