This trail-blazing volume covers nanoreactor essentials, including a review of synthetic procedures and materials used to develop various nanoreactor configurations. It explores nanoreactor theory and design, highlighting the fundamental differences between molecular events in macroscale and nanoscale reactors. The book offers a clear look at the dominating role of interfaces and how they affect nanoreactor properties and processes. Moreover, it shows how chemical reaction engineering can be applied in analyzing thermodynamics of self-assembly, colloidal stability, reaction kinetics and stochastic effects, and nanoreactor optimization. The book explores integrated nanoreactor systems, covering a theoretical treatment of how nanoreactors can be mobilized inside cells and tissues or as nanostructured films or coatings. Supported by over 100 diagrams and 250 equations, this definitive resource spotlights 14 bionanoreactor systems in development, including organic polymers, vesicles, polymer-stabilized liposomes, artificial protein cages, stem cells, DNA architectures, and others.For example, chemical modification of phenylalanine ammonia lyase (PAL) by pegylation produces a protected form of PAL ... Catalase, an enzyme which degrades hydrogen peroxide, a major product in the metastasis of cancer cells, ... it has little effect on targeting the enzyme to specific cells or tissues which may be most affected by enzyme malfunction. ... Direct administration of the enzyme into the cerebrospinal fluid also did not improve the accumulation of enzyme in the brain.
|Title||:||Nanoreactor Engineering for Life Sciences and Medicine|
|Publisher||:||Artech House - 2008|