The present Test Guideline addresses the human health hazard endpoint skin corrosion, following exposure to a test chemical. Skin corrosion is defined as the production of irreversible tissue damage, manifested as visible necrosis of the skin ...The skin discs are taken from humanely killed rats aged 28-30 days. Corrosive ... of the stratum corneum. The TER method utilizing rat skin has shown to be predictive of in vivo corrosivity in the rabbit assessed under OECD guideline 404 (3).
|Title||:||OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER)|
|Publisher||:||OECD Publishing - 2013-07-26|