Oxygen/Nitrogen Radicals and Cellular Injury

Oxygen/Nitrogen Radicals and Cellular Injury

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Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.These results suggest that nitric oxide (a#39;NO) is an important pathogenic mediator in tissue injury during exposure of animals to ... Catalase. Transgenic mice carrying a rat catalase transgene driven by the 5a#39; flanking sequence and promoter of the mouse ... of antioxidant enzymes can protect animals against a variety of tissue injury resulting from different oxidant insults. ... Because the defective gene will affect every single type of cell in the animals, the knockout mice may provide ananbsp;...

Title:Oxygen/Nitrogen Radicals and Cellular Injury
Author:Kenneth B. Adler, Robert D. Devlin, Val Vallyathan
Publisher:DIANE Publishing - 2000-03-01


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