Covers endothelial biology from the fundamentals of structure and lung fluid balance physiology to descriptions of the molecular mechanisms involved in the development of lung failure. This illustrated text provides the knowledge of endothelial function, vascular integrity, pulmonary function, and pathophysiology in respiratory failure.Actin microfilaments, along with microtubules, are activated following endothelial wounding to mediate repair and re-establish integrity. Within the first few hours post wounding, endothelial cells at the wound edge become polarized perpendicular to the ... In addition, dynamic focal adhesions to the substratum are turned over as the cell moves (Davies et al., 1994). ... to become activated migrating cells can be divided into three sequential stages (Figure 2) (Lee and Gotlieb, 2003a).
|Title||:||Perspectives on Lung Endothelial Barrier Function|
|Author||:||Carolyn E. Patterson|
|Publisher||:||Elsevier - 2005|