Pharmacology of Neurotransmitter Release

Pharmacology of Neurotransmitter Release

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It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.M2-deficient mice had problems in passive avoidance tests, demonstrating the role of this receptor subtype in learning and ... 2001). M3 AChR functions Mice with deletion of the M3 receptor gene were lean and consumed less food than theiranbsp;...

Title:Pharmacology of Neurotransmitter Release
Author:Thomas C. Südhof, Klaus Starke
Publisher:Springer Science & Business Media - 2007-12-07


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