Phylogenesis of Immune Functions

Phylogenesis of Immune Functions

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This volume discusses recent advances in research regarding the evolution of specific and nonspecific defense responses in a taxonomically diverse array of species. Topics regarding invertebrates include the protective mechanisms (cellular and molecular) employed by insects, the protective roles of lectins, and the self-nonself discrimination revealed by tissue incompatibility reactions. With vertebrates, the evolution of the immunoglobulin-related superfamily of recognition molecules (including immunoglobulins and the major histocompatibility complex molecules) is examined over several chapters. Other topics reviewed include the evolution of nonimmunoglobulin mediators of defense (e.g., cytokines and eicosanoids), lymphocyte subpopulations (including effects of ambient temperature on function) and the phylogenetic emergence of natural killer cells. Phylogenesis of Immune Functions provides invaluable information for evolutionary biologists, as well as all immunologists and other researchers interested in discovering how inhabitants in our increasingly threatened biosphere protect themselves against environmental pathogens and toxins.Although erythrocytes exhibit a very limited number of different sugars on the cell surface, the variety of linkages and ... Nevertheless, it is likely that additional lectins specific for carbohydrate structures less frequent than those found on the erythrocyte ... However, this is more a matter of how ubiquitous the ligand is rather than related to the intrinsic properties of the lectin ... In most cases the definition of the specificity of a lectin arises from practical criteria which do not reflect the actualanbsp;...

Title:Phylogenesis of Immune Functions
Author:Gregory W. Warr, Nicholas Cohen
Publisher:CRC Press - 1990-11-21


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