After a 10 mg. oral dose of hydrocodone bitartrate, a mean peak serum drug level of 23.6 ng/ml and an elimination half-life of 3.8 hours were found. ... The intensity of the syndrome does not always correlate with the duration of maternal opioid use or dose. ... Definitive diagnosis is made by spectroscopic analysis of water- diluted (1:100) blood specimen, which shows an abnormal band at 630 nm foranbsp;...
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