Introduces the principles that augment the formulation of products free from traditional preservatives by creating a hostile environment for microorganisms without diminishing quality. The text emphasizes that the preservation of a product should be inherent in the formula and examines the use of multifunctional chemicals whose secondary characteristics include germistatic and germicidal qualities.Amino acid chelating agents, such as EDTA, are anionic and react with cationic alkaline earth and heavy metal ions (i.e., copper, manganese, and iron ions) to form anionic ... Chelation of metal ions helps reduce hazing and color changes due to the reaction of metal ions with formula components. ... Although gram- positive bacteria do not exhibit significant sensitivity to EDTA, all organisms require iron.
|Title||:||Preservative-Free and Self-Preserving Cosmetics and Drugs|
|Author||:||Jon J. Kabara|
|Publisher||:||CRC Press - 1997-01-02|