qThis book is intended to introduce the field of phamacogenetics and pharmacogenomics to health care professionals. It brings together the latest informaiton about how human genetics impacts drug response phenotypes. It is written to enable the reader to undestand the current knowledge and challenges to the fieldq--Provided by publisher.A list of genetic associations identified by GWAS is summarized at http://www. genome.gov/gwastudies/. ... LINKAGE DISEQUILIBRIUM STRUCTURE IN POPULATIONS OF DIVERSE GEOGRAPHICAL ORIGIN The history of the population ... As distance from Africa increases, diversity in haplotype structure decreases, reflecting the origin of humans in Africa and ... are valuable for identifying a haplotype block, these same tag SNPs do not efficiently identify haplotype blocks in Africans.
|Title||:||Principles of Pharmacogenetics and Pharmacogenomics|
|Author||:||Russ B. Altman, David Flockhart, David B. Goldstein|
|Publisher||:||Cambridge University Press - 2012-01-23|