Probing Aptamer Specificity for Diagnostics

Probing Aptamer Specificity for Diagnostics

4.11 - 1251 ratings - Source

Theoretical studies focusing on the nature of landscapes that correlate molecular sequences to molecular function have mainly been carried out in silico due to the vast amounts of data that are needed for analysis. In vitro selections of aptamers are a good model system to study theoretical questions at a experimental level. With the introduction of robotic platforms that conduct in vitro selections, it is now capable of producing significant amounts of data in a short time, making theoretical modeling with real experimental data attainable.The reactions are performed as described by the vendora#39;s instructions. ... under vacuum and the pellets are resuspended in deionized formamide and developed on a CEQ 2000XL 8-channel capillary DNA sequencer (Beckman-Coulter).

Title:Probing Aptamer Specificity for Diagnostics
Author:Jennifer Fang En Lee
Publisher:ProQuest - 2007


You Must CONTINUE and create a free account to access unlimited downloads & streaming