Theoretical studies focusing on the nature of landscapes that correlate molecular sequences to molecular function have mainly been carried out in silico due to the vast amounts of data that are needed for analysis. In vitro selections of aptamers are a good model system to study theoretical questions at a experimental level. With the introduction of robotic platforms that conduct in vitro selections, it is now capable of producing significant amounts of data in a short time, making theoretical modeling with real experimental data attainable.The reactions are performed as described by the vendora#39;s instructions. ... under vacuum and the pellets are resuspended in deionized formamide and developed on a CEQ 2000XL 8-channel capillary DNA sequencer (Beckman-Coulter).
|Title||:||Probing Aptamer Specificity for Diagnostics|
|Author||:||Jennifer Fang En Lee|
|Publisher||:||ProQuest - 2007|