These studies convincingly demonstrate that PRRSV infection uniquely induces polyclonal B-cell activation, immunopathology and little to no repertoire diversification. With the benefits that the isolator piglet affords immunological studies, i.e. exclusion of maternal and environmental variables, PRRSV infection could serve as a model for examining mechanisms involved in causing viral infection-mediated B-cell dysregulation.A separate reference standard serum was used for determining anti-TNP and anti -FLU titers, thus ELISA Units of activity/mL ... of fit values 66 Treatment and analyses of blood samples Determination of IgG anti-PRRSV titers by IDEXX ELISA.
|Title||:||PRRSV Infection of Neonatal Piglets Induces Immune Dysregulation and Modulation|
|Author||:||Caitlin Danielle Lemke|
|Publisher||:||ProQuest - 2006|