Regenerative medicine for the repair of connective tissues is a fast moving field which generates a lot of interest. Unfortunately the biomaterials and biomechanics for soft tissue repair has been under-represented in the past. Particularly the natural association between cartilage, tendons and ligaments is often not made. Regenerative medicine and biomaterials for the repair of connective tissues addresses this gap in the market by bringing together the natural association of cartilage, tendons and ligaments to provide a review of the different structures, biomechanics and, more importantly, provide a clear discussion of practical techniques and biomaterials which may be used to repair the connective tissues. Part one discusses cartilage repair and regeneration with chapters on such topics as structure, biomechanics and repair of cartilage. Chapters in Part two focus on the repair of tendons on ligaments with particular techniques including cell-based therapies for the repair and regeneration of tendons and ligaments and scaffolds for tendon and ligament tissue engineering. Addresses the natural association between cartilage, tendons and ligaments which is often not made Provides a review of the different structures, biomechanics and practical techniques which are used in the repair of connective tissues Chapters focus on such areas as cartilage repair and regeneration, the repair of tendons and ligaments, investigating techniques including scaffolds and cell-based therapies(Wiseman et al., 2003). ... However the heterogeneous response may have been compounded by the use of tissue of different ages and unknown ... The chondrocytes were either seeded directly into 3D agarose constructs or were passaged up to four times at weekly intervals prior to ... On application of dynamic compression (15% strain at 1 Hz), chondrocytes at early passages (P1 and P2) exhibited aanbsp;...
|Title||:||Regenerative Medicine and Biomaterials for the Repair of Connective Tissues|
|Author||:||Charles Archer, Jim Ralphs|
|Publisher||:||Elsevier - 2010-01-12|