Since the 1980s, the U.S. military has used depleted uranium in munitions and in protective armor on tanks. Depleted uranium is a toxic heavy metal and is weakly radioactive. Concerns have been raised about the adverse health effects from exposure to depleted uranium that is aerosolized during combat. Some think it may be responsible for illnesses in exposed veterans and civilians. These concerns led the Army to commission a book, Depleted Uranium Aerosol Doses and Risks: Summary of U.S. Assessments, referred to as the Capstone Report that evaluates the health risks associated with depleted uranium exposure. This National Research Council book reviews the toxicologic, radiologic, epidemiologic, and toxicokinetic data on depleted uranium, and assesses the Army's estimates of health risks to personnel exposed during and after combat. The book recommends that the Army re-evaluate the basis for some of its predictions about health outcomes at low levels of exposure, but, overall, the Capstone Report was judged to provide a reasonable characterization of the exposure and risks from depleted uranium.(2003) with a cell-free system. ... (2007) re- ported results indicating the involvement of oxygen radicals in uranium-induced DNA damage. ... of the HPRT mutations induced by uranyl acetate exposure showed mutation spectra consistent, at least in part, with a chemical-induced effect. Uranyl ... (2007) reported evidence of a chemical mechanism by which uranium might alter DNA transcription and repair.
|Title||:||Review of Toxicologic and Radiologic Risks to Military Personnel from Exposure to Depleted Uranium During and After Combat|
|Author||:||Committee on Toxicology, Committee on Toxicologic and Radiologic Effects from Exposure to Depleted Uranium During and After Combat, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council|
|Publisher||:||National Academies Press - 2008-05-06|