This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.Linkage, Maps and QTL Rongling Wu, Changxing Ma, George Casella ... large effect, combined with many minor genes each with a small effect, determine the genetic variation of a quantitative trait (see ... one (P1) being homozygous for all increasing alleles and the second (P2) being homozygous for all decreasing alleles.
|Title||:||Statistical Genetics of Quantitative Traits|
|Author||:||Rongling Wu, Changxing Ma, George Casella|
|Publisher||:||Springer Science & Business Media - 2007-07-17|