Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the worldas foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. New information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Extracted and highlighted evidence levels. Medicine eBook is accessible on a variety of devices.For FFP, the following approximation can be applied: 10 mL/kg will reduce an INR of 4.2a2.4, an INR of 3.0a2.1 or an INR of 2.4a1.8; reducing an INR of 4.2a 1.4 would therefore require 40 mL/kg.260 Treatment must be combined with vitamin K1 (1a2 ... However, PCC seems to reverse anticoagulation faster than FFP.
|Author||:||James C. Grotta, Gregory W Albers, Joseph P Broderick, Scott E Kasner, Eng H Lo, A David Mendelow, Ralph L Sacco, Lawrence KS Wong|
|Publisher||:||Elsevier Health Sciences - 2015-07-10|