The Changing Nervous System : Neurobehavioral Consequences of Early Brain Disorders

The Changing Nervous System : Neurobehavioral Consequences of Early Brain Disorders

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This book provides an integrated review of current research on neural plasticity and reorganization after early cerebral insults. Addressing both animal studies and a variety of diverse clinical populations, including children with congenital brain malformations, focal lesions, autism, and pervasive developmental disorders, this book summarizes many of the major advances on neural plasticity made in these areas over the past several years. Characterized by a broad historical perspective including contributions from some of the earliest researchers on environmental factors and brain organization, the book advances the reader form the laboratory to application in several human populations. Many of the components of the book explicitly address relationships of animal and human models, showing that the laboratory and the clinic are overlapping settings, not isolated chambers as they are often perceived. The understanding of neural plasticity and both biological and environmental factors that influence brain reorganization after early cerebral insult has major implications for treatment. The book outlines many of the potential applications for treatment of early brain disorders. The contributors include basic neuroscientists, cognitive neuroscientists, and clinician-researchers who work together to bridge gaps among disciplines. The book should facilitate collaborative research and applications in the critical areas of neural plasticity and brain reorganization. Advancement of knowledge of factors that prevent and enhance brain reorganization after early cerebral insult is a key to unraveling the mysteries of the developmental disorders characteristic of children and which influence their development through adulthood.... to suppose that knowledge is built into the infant cortex in the form of detailed and well-specified synaptic connections, independent of and prior to the effects of input to the cortex (what Pinker [1997a] refers to as an innate aquot;wiring diagramaquot;).

Title:The Changing Nervous System : Neurobehavioral Consequences of Early Brain Disorders
Author:Sarah H. Broman Health Scientist Administrator National Institute of Neurological Disorders and Stroke, Houston Jack M. Fletcher Professor of Pediatrics University of Texas Health Sciences Center
Publisher:Oxford University Press, USA - 1999-07-12


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