Biotechnology has played an essential role in the development of the healthcare chemical industries. The range of product includes diagnostic, prophylactic and therapeutic agents. The discovery of a potentially active compound starts a sequence of exhaustive chemical and biological testing that may culminate in manufacture of the agent or an improved analog. The role of biotechnology in this complex path to regulatory approval and marketing is diverse. Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bio products. Biotechnology also utilizes these products for manufacturing purpose. Some of the examples of drugs produced through biotechnology are penicillin, lincomycin, streptomucin, tylosin, peptide antibiotics, cephalosporins, etc. Modern use of similar terms includes genetic engineering as well as cell and tissue culture technologies. Biotechnology draws on the pure biological sciences and in many instances is also dependent on knowledge and methods from outside the sphere of biology. Conversely, modern biological sciences are intimately entwined and dependent on the methods developed through biotechnology and what is commonly thought of as the life sciences industry. The development of biotechnology is taking place in almost all fields of human life. The recent advances in the field of basic genetics have opened up new vistas, potentials and possibilities. Some of the fundamentals of the book are the pharmaceutical industries, marketing strategy, common features in the evolution of products and processes, process technology fermentation, product recovery, new trends in biotechnology, penicillins, biosynthesis and regulation of thienamycin, olivanic acids and epithienamycins, aminoglycoside antibiotics, streptidine and deoxystreptamine, streptomycin, neomycin, paromomycin, ribostamycin and, butirosin gentamicin, micronomicin and sisomicin, tylosin, peptide antibiotics, current applications of peptides, blasticidin S: an agricultural antibiotic bleomycin and bestatin: peptides used in anticancer therapy etc. The present book contains process of biotechnology based bulk drugs like penicillin, B lactam antibiotics, aminoglycoside antibiotics, peptide antibiotics, anti cancer agents, lincomycin etc. This is very resourceful book for entrepreneurs, technocrats, research scholars, libraries etc.Table 20: Elemental Composition of Penicillin G Element Potassium salt Free acid C 51.6 57.6 H 4.6 5.2 K 10.5 _ N 7.5 8.4 O 17.2 19.2 S 8.6 9.6 MW 372.47 333.38 Table 21 : Raw Material Prices, Composition, etc. US cost % % Item ($kga 1)anbsp;...
|Title||:||The Complete Book on Biotechnology Based Bulk Drugs|
|Author||:||NPCS Board of Consultants & Engineers|
|Publisher||:||NIIR PROJECT CONSULTANCY SERVICES - 2007-01-01|