The Enzymes of Biological Membranes

The Enzymes of Biological Membranes

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In the first edition of The Enzymes of Biological Membranes, published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975. This was a period of transition from the romantic phase of membrane biochemistry, preoccupied with conceptual developments and the general properties of membranes, to an era of mounting interest in the specific properties of membrane-linked enzymes analyzed from the viewpoints of modem enzymology. The level of sophistication in various areas of membrane research varied widely; the structures of cytochrome c and cytochrome b were known s to atomic detail, while the majority of membrane-linked enzymes had not even been isolated. In the intervening eight years our knowledge of membrane-linked enzymes ex panded beyond the wildest expectations. The purpose of the second edition of The Enzymes of Biological Membranes is to record these developments. The first volume describes the physical and chemical techniques used in the analysis of the structure and dynamics of biological membranes. In the second volume the enzymes and met abolic systems that participate in the biosynthesis of cell and membrane components are discussed. The third and fourth volumes review recent developments in active transport, oxidative phosphorylation, and photosynthesis.The Channels in the F1 Fo It seems highly improbable that the channel of the Fo portion of the ATP-synthase particle is the only ... Additionally, the work of Carlsson and Ernster (1981a, b) indicates strongly that there is a proton- accessibility barrier associated with the isolated F1. ... the O2-generating sites of chloroplasts have one property which they do not share with the ATPase or ATP- synthase proton channel. ... An energized acidic proton then diffuses downhill in the membrane.

Title:The Enzymes of Biological Membranes
Author:Anthony Martonosi
Publisher:Springer Science & Business Media - 2013-03-09


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