Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options.Hum Mol Genet 2004; 13(21):2633-2645. 7. Sapru MK, Yates JW, Hogan ... Intraarterial delivery of naked plasmid DNA expressing full-length mouse dystrophin in the mdx mouse model of duchenne muscular dystrophy. Hum Gene Ther 2004;anbsp;...
|Title||:||The Sarcomere and Skeletal Muscle Disease|
|Author||:||Nigel G. Laing|
|Publisher||:||Springer Science & Business Media - 2009-09-29|