This book describes statistical techniques for the design and evaluation of research studies on medical diagnostic tests, screening tests, biomarkers and new technologies for classification and prediction in medicine. Based on solid mathematical theory, the book includes worked examples along with data and code, which provides the reader with easy implementation of methods.Result 6.3 In large samples , MD (5151 (t) -a 351(0) has a mean zero normal distribution with variance 02(t) = t(1 a t)/{fD(SBI(t))}2, where fD(y) is the probability density of ... A more flexible form will presumably yield a more variable estimator.

Title | : | The Statistical Evaluation of Medical Tests for Classification and Prediction |

Author | : | Margaret Sullivan Pepe |

Publisher | : | Oxford University Press, USA - 2003 |

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