Statin use has been associated with non-Hodgkin lymphoma (NHL) although results have been inconsistent. Data from two population-based case-control NHL studies in the San Francisco Bay Area that included incident cases diagnosed from 1988-1993 (NHL1, cases=1591, controls=2515) and 2001-2006 (NHL2, cases=2078, controls=2081) were used to investigate the association between risk of NHL and NHL subtypes, and statin use. Genetic data were analyzed to investigate polymorphisms in genes in pathways that may be affected by statins' disruption of cholesterol synthesis.cholesterol ?aquot; A cue card that provided a list of the generic and brand names of cholesterol-lowering drugs commonly prescribed in the U.S. to lower blood cholesterol levels (and all statin medications approved in the U.S. during this time anbsp;...
|Title||:||Use of 3-hydroxy-3-methylglutaryl Coenzyme-A Reductase Inhibitors (statins), Genetic Polymorphisms in Immunomodulatory and Inflammatory Pathways and Risk of Non-Hodgkin Lymphoma|
|Author||:||Paige Marie Bracci|
|Publisher||:||ProQuest - 2007|