In Viral Membrane Proteins: Structure, Function, and Drug Design, Wolfgang Fischer summarizes the current structural and functional knowledge of membrane proteins encoded by viruses. In addition, contributors to the book address questions about proteins as potential drug targets. The range of information covered includes signal proteins, ion channels, and fusion proteins. This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.Therefore, disregarding potential downstream events, binding of Lck to CD4 and Nef does not seem to be competitive. ... Mapping of the Nef Interaction Site on Lck SH3 LckU3 residues that are affected upon Nef binding (Figure 18.7) are essentially those reported in similar investigations of SH3 domain interactions with poly-proline peptides (Larson and Davidson, 2000), and are in general accordanceanbsp;...
|Title||:||Viral Membrane Proteins: Structure, Function, and Drug Design|
|Author||:||Wolfgang B. Fischer|
|Publisher||:||Springer Science & Business Media - 2007-08-02|