Voltage-Gated Ion Channels as Drug Targets

Voltage-Gated Ion Channels as Drug Targets

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Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.Res., 2003, 93, 744a€“751. Nissan, Chroman derivatives, WO 9804542, 1998. Nissan, Chroman derivatives, WO 0058300, 2000. Nissan, 4-Oxybenzopyran derivatives, WO 0125224, 2001. Nissan, 4-Oxybenzopyran derivatives, WO 0121609, anbsp;...

Title:Voltage-Gated Ion Channels as Drug Targets
Author:David J. Triggle, Murali Gopalakrishnan, David Rampe, Wei Zheng
Publisher:John Wiley & Sons - 2006-08-21


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